CAT#: 0543-P150-0.1MG

Pactamycin

High-purity Pactamycin for microbiology and molecular research applications.

Size: 0.1 mg

Purity: >95% by HPLC

Dry Ice: No

Hazardous: No

Shipping: Ambient

Storage: -20°C

Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.

Description

Pactamycin (syn: Pactacin) is a unique type of highly-substituted aminocyclitol produced by Streptomyces sp. It is a potent inhibitor of translation in eukaryotes, bacteria and archaea, and is active against Gram-positive and Gram-negative bacteria.

Pactamycin was patented by Upjohn Inc. in 1967 as an antiviral. It binds to the 30S ribosomal subunit at a site distinct from tetracycline and hygromycin B, promoting structural changes that prevent tRNA from binding. Pactamycin also exhibits antineoplastic and antimalarial properties. Although its use was limited by toxicity, some semisynthetic analogs are less toxic.

Product Information

CAS Number	23668-11-3
Molecular Formula	C28H38N4O8
Molecular Weight	558.6
Applications	Microbiology
Purity	>95% by HPLC
Shipping Conditions	Ambient
Storage Conditions	-20°C

Research Use Only. This product is intended for laboratory research applications. Not for use in diagnostic procedures.

Molecular Visualization · PubChem

Pactamycin

Explore the chemical structure of Pactamycin in two dimensions and interact with its three-dimensional molecular model. Rotate, zoom and inspect the molecular geometry.

PubChem Compound ID 5289124

Molecular formula Loading...

Molecular weight Loading...

2D Chemical Structure

Two-dimensional molecular diagram from PubChem

Loading the chemical diagram...

3D Molecular Structure

Interactive 3D conformer · Drag to rotate · Scroll to zoom

Loading the 3D molecular model...

Data source: PubChem — Pactamycin, CID 5289124
Molecular data are requested from the PubChem PUG REST API. The 3D view requires a 3D conformer to be available from the API. A computed conformer is not necessarily an experimentally determined molecular structure.