Interferon Gamma (IFN-γ) Recombinant Protein
Interferon Gamma (IFN-γ) is a biologically active recombinant cytokine widely used in immunology, cell biology, oncology, microbiology, and infectious disease research. As a member of the Type II interferon family, IFN-γ regulates both innate and adaptive immune responses by activating macrophages, stimulating Natural Killer (NK) cells, enhancing antigen presentation, and supporting T-cell mediated immunity. High-purity recombinant IFN-γ protein is an essential research reagent for studying cytokine signaling, inflammation, host-pathogen interactions, and immune regulation.
Key Features
- Recombinant Interferon Gamma (IFN-γ)
- Research Grade Protein
- High Purity (>97%)
- Low Endotoxin
- Biologically Active
- Sterile Filtered
- Lyophilized Powder
- Suitable for Cell Culture
Research Applications
- Immunology Research
- Cytokine Signaling
- Cancer Immunology
- Macrophage Activation
- NK Cell Studies
- T Cell Research
- Inflammation Research
- Drug Discovery
Advantages
- Excellent Batch Consistency
- High Biological Activity
- Reliable Experimental Results
- Easy Reconstitution
- Long-Term Stability
- Optimized for Laboratory Research
- Suitable for Functional Assays
- Quality Tested
Product Overview
Interferon Gamma (IFN-γ), also known as IFNG, is an essential cytokine involved in regulating immune defense against viral infections, intracellular pathogens, and tumor cells. Produced naturally by activated T lymphocytes and Natural Killer cells, IFN-γ coordinates communication between immune cells and promotes the activation of macrophages, enhances antigen presentation, and stimulates multiple immune signaling pathways.
Recombinant Interferon Gamma protein is widely used as a research reagent in molecular biology and biomedical laboratories. Scientists utilize IFN-γ to investigate immune cell activation, inflammatory signaling, cytokine interactions, antiviral responses, and mechanisms involved in autoimmune diseases and cancer immunology. High biological activity and exceptional purity make recombinant IFN-γ an ideal choice for reproducible laboratory experiments.
Biological Functions
- Activates macrophages
- Stimulates Natural Killer (NK) cell activity
- Enhances antigen presentation
- Promotes Th1 immune responses
- Supports antiviral immunity
- Regulates cytokine production
- Contributes to tumor immune surveillance
- Participates in antibacterial defense
- Controls inflammatory signaling pathways
- Supports adaptive immune responses
Product Specifications
| Property | Specification |
|---|---|
| Product | Recombinant Interferon Gamma (IFN-γ) |
| Synonyms | Interferon Gamma, IFN Gamma, IFNG |
| Protein Family | Type II Interferon |
| Expression System | E. coli |
| Molecular Weight | Approximately 16.7 kDa |
| Purity | >97% |
| Biological Activity | Fully biologically active |
| Endotoxin | <0.1 EU/μg |
| Appearance | Sterile filtered white lyophilized powder |
| Storage | -20°C to -80°C |
Common Research Applications
- Cell Culture Experiments
- Flow Cytometry
- ELISA Development
- Protein Function Studies
- Immune Cell Stimulation
- Macrophage Polarization
- Cancer Biology
- Host-Pathogen Interaction Studies
- Signal Transduction Research
- Biomarker Discovery
- Inflammatory Disease Research
- Infectious Disease Studies
- Virology Research
- Translational Immunology
- Drug Screening
Storage & Reconstitution
Store the lyophilized recombinant protein between -20°C and -80°C. Before opening, briefly centrifuge the vial to collect the contents at the bottom. Reconstitute the protein using sterile distilled water or an appropriate aqueous buffer containing 0.1% BSA to obtain the desired concentration. Divide into working aliquots after reconstitution and avoid repeated freeze-thaw cycles to preserve biological activity.
Quality Control
- SDS-PAGE Purity Analysis
- HPLC Verification
- Biological Activity Testing
- Endotoxin Testing
- Sterility Control
- Protein Concentration Verification
- Batch-to-Batch Consistency
- Research Quality Validation
Research Use Only (RUO)
This recombinant Interferon Gamma (IFN-γ) protein is intended exclusively for laboratory research applications, including immunology, molecular biology, cell biology, oncology, microbiology, and related scientific studies. It is not intended for diagnostic, therapeutic, or clinical use.